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Table 2 Combined efficacy results.

From: Impact of hormonal treatment duration in combination with radiotherapy for locally advanced prostate cancer: Meta-analysis of randomized trials

Outcomes

Pts (RCTs)

RR (95% CI)

p-value

Het. (p)

AD (%)

NNT

BF

3,424 (5)

1.32 (1.09, 1.60)

0.004

0.003

10.1

9-10

CSS

3,128 (4)

1.21 (0.82, 1.79)

0.32

0.09

-

-

OS

3,128 (4)

1.09 (0.92, 1.28)

0.28

0.15

-

-

DM

2,852 (3)

1.77 (1.16, 2.69)

0.007

0.06

11.5

9

LR

2,852 (3)

1.87 (1.22, 2.86)

0.004

0.10

11.7

9

  1. Pts: patients; RCTs: randomized clinical trials; RR: relative risk; CI: confidence intervals; Het.: heterogeneity; p: p-value; AD: absolute difference; NNT: number needed to treat; BF: biochemical failure; CSS: cancer specific survival; OS: overall survival: LR: local relapse; DM: distant metastases.