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Figure 6 | BMC Cancer

Figure 6

From: Activating transcription factor-3 (ATF3) functions as a tumor suppressor in colon cancer and is up-regulated upon heat-shock protein 90 (Hsp90) inhibition

Figure 6

Effect of ATF3 down-regulation on peritoneal tumor growth and dissemination in vivo. Transfected human colon cancer cells (HCT116) were implanted into the peritoneal cavity. A) Down-regulation of ATF3 promoted peritoneal carcinomatosis formation, as determined by counting peritoneal nodules (*P < 0.05). B) Representative images of peritoneal dissemination in the ATF3-shRNA group.

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