Table 3 Multivariate analysis of disease-free survival (DFS) and overall survival (OS)
From: The invasive lobular carcinoma as a prototype luminal A breast cancer: A retrospective cohort study
DFS | OS | |||||
|---|---|---|---|---|---|---|
HR | 95% CI | P | HR | 95% CI | P | |
Age (<35 yrs) | 2.17 | (1.55-3.02) | <0.001 | 1.96 | (1.27-3.02) | 0.002 |
pT (≥T2) | 1.85 | (1.44-2.37) | <0.001 | 1.72 | (1.24-2.40) | 0.001 |
pN (positive) | 2.81 | (2.15-3.68) | <0.001 | 2.61 | (1.84-3.69) | <0.001 |
M (1) | · | · | · | 10.75 | (6.29-18.37) | <0.001 |
Subtype | ||||||
LA-IDC | 1 (ref) | 1 (ref) | ||||
non LA-IDC | 1.69 | (1.23-2.33) | 0.001 | 1.5 | (0.97-2.33) | 0.07 |
ILC | 0.77 | (0.31-1.90) | 0.57 | 0.75 | (0.18-3.09) | 0.7 |
p53 (>25%) | 1.27 | (0.96-1.66) | 0.09 | 1.64 | (1.17-2.31) | 0.004 |
Ki-67 (≥20%) | 1.06 | (0.81-1.39) | 0.67 | 1.08 | (0.77-1.50) | 0.67 |
Operation (mastectomy) | 1.15 | (0.89-1.48) | 0.29 | 1.14 | (0.82-1.59) | 0.44 |
Hormone therapy (no) | 1.19 | (0.88-1.62) | 0.25 | 1.81 | (1.21-2.71) | 0.004 |