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Table 1 Patient and tumor characteristics No metastases (M0), Peritoneal Metastases (PM) and Liver Metastases (LM) patients

From: Specific genomic aberrations in primary colorectal cancer are associated with liver metastases

  

M0

  

PM

  

LM

  

p-value**

  

25

Percentage

 

37

Percentage

 

36

Percentage

  

Gender

Male

14

56%

 

21

57%

 

27

75%

  
 

Female

11

44%

 

16

43%

 

9

25%

 

0,185

Mean age at diagnosis

   

64,21

  

53,23

  

54,66

 

Location primary tumor

Right colon

11

44%

 

11

30%

 

4

11%

  
 

Left colon

9

36%

 

22

59%

 

22

61%

  
 

Rectum

5

20%

 

4

11%

 

10

28%

 

0,027

T-status

T1

0

0%

 

0

0%

 

0

0%

  
 

T2

0

0%

 

1

3%

 

4

11%

  
 

T3

21

84%

 

25

67%

 

30

84%

  
 

T4

4

16%

 

11

30%

 

1

3%

 

0,01

 

unknown

0

0%

 

0

0%

 

1

3%

  

N-status

N0

19

76%

 

17

47%

 

13

36%

  
 

N+

6

24%

 

19

53%

 

22

61%

 

0,01

 

unknown

0

0%

 

0

0%

 

1

3%

  

Stage

1

0

0%

 

1

3%

 

0

0%

  
 

2

16

64%

 

5

13%

 

3

8%

  
 

3

9

36%

 

13

35%

 

7

20%

  
 

4

0

0%

 

18

49%

 

26

72%

 

0

Presentation

          

0,009

 

Metachrone

25

100%

 

19

51%

 

8

22%

  
 

Synchrone

   

18

49%

 

26

72%

  
 

Unknown

   

0

0%

 

2

6%

 

1,00E-06

Differentiation

Good

0

0%

 

3

8%

 

3

12%

  
 

Moderate

21

88%

 

27

73%

 

17

65%

  
 

Poor

3

13%

 

5

14%

 

6

23%

  
 

Other type

0

0%

 

2

5%

 

0

0%

 

0,3

Overall survival

           

Median in months (range)

   

103 (12-279)

  

22 (2-120)

  

26 (0-108)

 

MSI status

Stable

21

91%

 

33

97%

 

30

100%

  
 

Low

2

9%

 

0

0%

 

0

0%

  
 

High

0

0%

 

1

3%

 

0

0%

 

0,124

Adjuvant treatment

No

16

64%

 

25

68%

 

34

94%

  
 

Chemo

6

24%

 

12

32%

 

2

6%

  
 

Unknown

3

12%

 

0

0%

 

0

0%

 

0,014

  1. ** = Pearson Chi-Square Test
  2. MSI status = Micro Satellite Instability status