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Table 5 Survival fractions of glioma cells in different groups

From: Boron neutron capture therapy induces apoptosis of glioma cells through Bcl-2/Bax

Group

Survival fraction (%)

 

U87

U251

SHG44

Unirradiated control (A)

100

100

100

Irradiated in 60Co by 4 Gy (B)

68.1

63.7

64.5

Irradiated in 60Co by 8 Gy (C)

10.9

13.6

12.4

Irradiated in reactor for the same treatment period as used for Group D (F)

3.1

2.3

2.5

Irradiated in reactor for the same treatment period as used for Group E (G)

1.6

1.4

1.6

Irradiated in reactor by 4 Gy (H)

2.9

2.2

2.6

Irradiated in reactor by 8 Gy (I)

1.4

0.9

1.2

Irradiated in reactor with BNCT by 4 Gy (D)*

< 0.01%

< 0.01%

< 0.01%

Irradiated in reactor with BNCT by 8 Gy (E)**

< 0.01%

< 0.01%

< 0.01%

  1. *P < 0.01 vs A, B, F and H **P < 0.01 vs A, C, G, I and D