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Table 2 Cox regression analyses by molecular subgroup, by immunohistochemistry

From: Long-term survival of women with basal-like ductal carcinoma in situ of the breast: a population-based cohort study

  All (n = 392) Breast Conserving Surgery (n = 298)
  Univariate HR
(95% CI)
Adjusted* HR
(95% CI)
Univariate HR
(95% CI)
Adjusted* HR
(95% CI)
  Event: local recurrence (n = 76)
Gene-expression classification     
   Non basal-like (n = 360) 1 (Reference) 1 1 1
   Basal-like (n = 32) 1.7 (0.8-3.8) 1.9 (0.8-4.2) 1.6 (0.7-3.6) 1.8 (0.7-4.2)
Triple-negative classification     
   Non triple-negative (n = 377) 1 (Reference) 1 1 1
   Triple-negative (n = 32) 1.1 (0.4-2.7) 1.1 (0.4-2.9) 1.0 (0.4-2.7) 1.0 (0.3-2.9)
Tumor grade     
   I (n = 30) 1 (Reference) 1 1 1
   II (n = 182) 1.2 (0.4-3.4) 1.4 (0.5-4.0) 1.3 (0.5-3.9) 1.4 (0.5-3.9)
   III (n = 176) 1.0 (0.3-2.9) 1.3 (0.5-3.9) 1.4 (0.5-4.0) 1.4 (0.5-4.2)
Postoperation radiotherapy     
   No (n = 252) 1 (Reference) 1 1 1
   Yes (n = 140) 0.9 (0.5-1.5) 0.7 (0.4-1.3) 0.8 (0.4-1.4) 0.7 (0.4-1.4)
  Event: invasive- and general recurrence (n = 47)
Gene-expression classification     
   Non basal-like (n = 360) 1 (Reference) 1 1 1
   Basal-like (n = 32) 2.0 (0.8-5.0) 1.9 (0.7-5.1) 2.2 (0.8-5.6) 2.3 (0.8-6.1)
Triple-negative classification     
   Non triple-negative (n = 377) 1 (Reference) 1 1 1
   Triple-negative (n = 32) 1.4 (0.5-4.0) 1.6 (0.6-4.8) 1.7 (0.6-4.9) 2.1 (0.7-6.3)
Tumor grade     
   I (n = 30) 1 (Reference) 1 1 1
   II (n = 182) 1.0 (0.3-3.3) 1.1 (0.3-3.8) 1.1 (0.3-3.8) 1.1 (0.3-3.8)
   III (n = 176) 0.7 (0.2-2.4) 1.1 (0.3-3.9) 0.9 (0.2-3.1) 1.0 (0.3-3.9)
Postoperation radiotherapy     
   No (n = 252) 1 (Reference) 1 1 1
   Yes (n = 140) 0.8 (0.4-1.6) 0.7 (0.3-1.5) 0.7 (0.3-1.4) 0.7 (0.3-1.6)