| |
Sens.
|
Spec.
|
AUC
|
OR
|
95%CI
|
PPV
|
NPV
|
P(chi2)
|
|---|
|
hTERT
|
62.5
|
72.9
|
0.68
|
4.48
|
2.09-9.58
|
71.4
|
64.2
|
< 0.001
|
|
PPP1CA
|
68.8
|
62.7
|
0.66
|
3.7
|
1.76-7.77
|
66.7
|
64.9
|
< 0.001
|
|
SENP1
|
56.3
|
78
|
0.67
|
4.55
|
2.08-9.94
|
73.5
|
62.2
|
< 0.001
|
|
MCM5
|
62.5
|
65.9
|
0.64
|
3.21
|
1.36-7.62
|
68.2
|
60
|
0.008
|
|
Cytology ALL*
|
41.7
|
87.9
|
0.65
|
5.2
|
2.06-13.1
|
78.1
|
59.3
|
< 0.001
|
|
Cytology Gr.2-3(Cyt2-3)
|
48.3
|
79.3
|
0.64
|
3.59
|
1.6-8
|
70.7
|
59.7
|
0.002
|
|
Cyt2-3+hTERT**
|
73.3
|
74.1
|
0.74
|
7.88
|
3.49-17.8
|
74.6
|
72.9
|
< 0.001
|
|
Cyt2-3+MCM5**
|
77.8
|
67.5
|
0.73
|
7.27
|
2.8-18.9
|
72.9
|
73
|
< 0.001
|
|
Cyt2-3+ SENP1**
|
65
|
74.1
|
0.70
|
5.32
|
2.42-11.7
|
72.2
|
67.2
|
< 0.001
|
|
Cyt2-3+PPP1CA**
|
75
|
60.3
|
0.68
|
4.57
|
2.09-9.96
|
66.2
|
70
|
< 0.001
|
|
Cyt2-3+MCM5+hTERT***
|
77.8
|
67.5
|
0.73
|
7.27
|
2.8-18.9
|
72.9
|
73
|
< 0.001
|
- * All atypical cells in the urine recorded as positive.
- ** One or both positive.
- *** If only hTERT was positive then the combined score was classified as negative.
