Table 3 Sensitivity and specificity of the urine markers when using cystoscopy as gold standard for detection of bladder cancer

hTERT

62.5

72.9

0.68

4.48

2.09-9.58

71.4

64.2

< 0.001

PPP1CA

68.8

62.7

0.66

3.7

1.76-7.77

66.7

64.9

< 0.001

SENP1

56.3

78

0.67

4.55

2.08-9.94

73.5

62.2

< 0.001

MCM5

62.5

65.9

0.64

3.21

1.36-7.62

68.2

60

0.008

Cytology ALL*

41.7

87.9

0.65

5.2

2.06-13.1

78.1

59.3

< 0.001

Cytology Gr.2-3(Cyt2-3)

48.3

79.3

0.64

3.59

1.6-8

70.7

59.7

0.002

Cyt2-3+hTERT**

73.3

74.1

0.74

7.88

3.49-17.8

74.6

72.9

< 0.001

Cyt2-3+MCM5**

77.8

67.5

0.73

7.27

2.8-18.9

72.9

73

< 0.001

Cyt2-3+ SENP1**

65

74.1

0.70

5.32

2.42-11.7

72.2

67.2

< 0.001

Cyt2-3+PPP1CA**

75

60.3

0.68

4.57

2.09-9.96

66.2

70

< 0.001

Cyt2-3+MCM5+hTERT***

77.8

67.5

0.73

7.27

2.8-18.9

72.9

73

< 0.001