Table 1 Expression and regulation of PFKFB2 in different lymphoid systems1
| Â | Expression (mE-value) | Regulation (mM-value) | Regulation (mM-value) | |||
|---|---|---|---|---|---|---|
samples | 15A | 15B | 15A 6/8 h | 15A 24 h | 15B 6/8 h | 15B 24 h |
T-ALL (6) | 6.3 ± 1.5 | 4.0 ± 1.9 | 1.7 ± 1.5 | 2.4 ± 1.4 | 1.9 ± 2.3 | 2.7 ± 2.3 |
Precursor B-ALL (25) | 4.6 ± 2.7 | 3.0 ± 1.7 | 0.7 ± 0.8 | 1.1 ± 1.2 | 0.6 ± 0.9 | 0.9 ± 1.1 |
   - hyperdiploid (7) | 2.1 ± 0.7 | 1.5 ± 0.2 | 0.7 ± 0.6 | 0.9 ± 1.1 | 0.3 ± 0.4 | 0.3 ± 0.3 |
   - EVT6/RUNX1 (10) | 6.7 ± 1.7 | 4.4 ± 1.5 | 0.5 ± 1.1 | 0.8 ± 1.5 | 0.8 ± 1.1 | 1.1 ± 1.2 |
   - others (8) | 4.2 ± 2.7 | 2.4 ± 1.3 | 0.9 ± 0.8 | 1.5 ± 0.8 | 0.6 ± 0.8 | 1.3 ± 1.2 |
Non-leukemic donors (6*) | 3.4 ± 0.2 | 2.0 ± 0.4 | 0.5 ± 0.7 | ND | 0.2 ± 0.3 | ND |
CEM-C7H2-S-lines (6) | 2.3 ± 0.1 | 1.8 ± 0.1 | 3.1 ± 0.9 | ND | 1.8 ± 0.4 | ND |
CEM-C7H2-R-lines (6) | 2.7 ± 0.3 | 1.8 ± 0.1 | 2.0 ± 2.0 | ND | 1.6 ± 1.3 | ND |