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Table 4 Reduction in biopsies/cancers detected using as a threshold for biopsy a 20% or higher probability of cancer.

From: A panel of kallikrein markers can predict outcome of prostate biopsy following clinical work-up: an independent validation study from the European Randomized Study of Prostate Cancer screening, France

 

No. biopsies

No. cancers:

No. high grade cancers:

 

Performed

Avoided

Found

Missed

Found

Missed

Biopsy all men at risk

1000

0 (0%)

317

0 (0%)

175

0 (0%)

Biopsy if >= 20% risk from full model

508

492 (49%)

256

61 (19%)

163

12 (4%)

  1. Numbers are given per 1000 men with elevated PSA (>= 3 ng/ml) and recommended for biopsy after clinical work-up.