Table 4 Haematological & Non-haematological toxicity per treatment arm
|
DC (n = 67) |
D (n = 65) |
DC (n = 67) |
D (n = 65) | P-value | |||||
|---|---|---|---|---|---|---|---|---|---|
| GrIII | GrIII | GrIV | GrIV | ||||||
| N | % | N | % | N | % | N | % | ||
| Neutropenia | 7 | 10.4 | 3 | 4.6 | 4 | 6.0 | 1 | 1.5 | 0.098 |
| Anaemia | 3 | 4.5 | - | - | - | - | - | - | 0.791 |
| Thrombocytopenia | 2 | 3.0 | - | - | - | - | - | - | < 0.001 |
| Febrile neutropenia | - | - | - | - | - | - | - | - | |
| Nausea | - | - | - | - | - | - | - | - | 0.128 |
| Vomiting | - | - | - | - | - | - | - | - | 0.999 |
| Diarrhoea | 2 | 3.0 | 1 | 1.5 | 1 | 1.5 | - | - | 0.999 |
| Stomatitis | - | - | - | - | - | - | - | - | 0.027 |
| Constipation | - | - | - | - | - | - | - | - | 0.274 |
| Neuromuscular | - | - | - | - | - | - | - | - | 0.999 |
| Neurosensory | - | - | - | - | - | - | - | - | 0.678 |
| Allergy | 2 | 3.0 | - | - | - | - | 1 | 1.6 | 0.680 |
| Fatigue | - | - | 6 | 9.2 | - | - | 1 | 1.5 | 0.015 |
| Oedema | - | - | - | - | - | - | - | - | 0.680 |
| Other | 0.999 | ||||||||
