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Table 1 Demographic and clinicopathological features of cases

From: COX-2 activation is associated with Akt phosphorylation and poor survival in ER-negative, HER2-positive breast cancer

   N %
ER Status Negative 102 41%
  Positive 145 59%
HER2 Status Negative 106 43%
  Weak 48 19%
  Moderate 51 21%
  High 42 17%
TNM Stage < = II 184 71%
  > = III 44 29%
Grade 1 or 2 108 50%
  3 107 50%
COX-2 Negative 75 30%
  Weak 83 34%
  Moderate 65 26%
  High 25 10%
pAkt Ser473 Negative 17 7%
  Weak 29 12%
  Moderate 59 24%
  High 142 57%
pAkt Thr308 Negative 14 6%
  Weak 24 10%
  Moderate 71 29%
  High 134 55%
pCaspase9 Ser196 Negative 38 15%
  Weak 30 12%
  Moderate 73 30%
  High 106 43%
pBAD Ser136 Negative 43 18%
  Weak 41 17%
  Moderate 76 31%
  High 85 34%
Survival Alive 159 64%
  Death from breast cancer 78 32%
  Death from other causes 11 4%
Race AA 143 58%
  EA 105 42%
p53 mutation Negative 200 81%
  Positive 48 19%
Chemotherapy No 99 43%
  Yes 132 57%
   mean ± SD
Age at Diagnosis (n = 248) 55.0 ± 13.9
Body mass index1 (n = 236) 29.0 ± 8.1
CD31 (n = 208) 49.1 ± 43.9
  1. 1 At time of hospital admission