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Table 1 Demographic and clinicopathological features of cases

From: COX-2 activation is associated with Akt phosphorylation and poor survival in ER-negative, HER2-positive breast cancer

  

N

%

ER Status

Negative

102

41%

 

Positive

145

59%

HER2 Status

Negative

106

43%

 

Weak

48

19%

 

Moderate

51

21%

 

High

42

17%

TNM Stage

< = II

184

71%

 

> = III

44

29%

Grade

1 or 2

108

50%

 

3

107

50%

COX-2

Negative

75

30%

 

Weak

83

34%

 

Moderate

65

26%

 

High

25

10%

pAkt Ser473

Negative

17

7%

 

Weak

29

12%

 

Moderate

59

24%

 

High

142

57%

pAkt Thr308

Negative

14

6%

 

Weak

24

10%

 

Moderate

71

29%

 

High

134

55%

pCaspase9 Ser196

Negative

38

15%

 

Weak

30

12%

 

Moderate

73

30%

 

High

106

43%

pBAD Ser136

Negative

43

18%

 

Weak

41

17%

 

Moderate

76

31%

 

High

85

34%

Survival

Alive

159

64%

 

Death from breast cancer

78

32%

 

Death from other causes

11

4%

Race

AA

143

58%

 

EA

105

42%

p53 mutation

Negative

200

81%

 

Positive

48

19%

Chemotherapy

No

99

43%

 

Yes

132

57%

  

mean ± SD

Age at Diagnosis

(n = 248)

55.0 ± 13.9

Body mass index1

(n = 236)

29.0 ± 8.1

CD31

(n = 208)

49.1 ± 43.9

  1. 1 At time of hospital admission