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Table 3 Multivariate Survival Analysis

From: Racial differences in treatment and survival in older patients with diffuse large B-cell lymphoma (DLBCL)

   All Cause (4,188 deaths) NHL (2,366 deaths) Other/Unknown Cause (1,822 deaths)
   HR p-value 95% CI HR p-value 95% CI HR p-value 95% CI
Age              
  66-< 70 ref.            
  70-< 75 1.38 < 0.0001 1.22 1.55 1.37 < 0.001 1.16 1.61 1.38 < 0.001 1.15 1.66
  75-< 80 1.75 < 0.0001 1.55 1.96 1.75 < 0.0001 1.50 2.05 1.72 < 0.0001 1.44 2.05
  ≥ 80 2.69 < 0.0001 2.41 3.00 2.60 < 0.0001 2.24 3.01 2.79 < 0.0001 2.36 3.29
Gender              
  Female ref.            
  Male 1.09 < 0.01 1.03 1.16 1.05 0.22 0.97 1.14 1.14 0.01 1.04 1.25
Race              
  White ref.            
  Black 1.24 0.01 1.06 1.46 1.16 0.19 0.93 1.45 1.35 0.01 1.06 1.71
  Other 1.09 0.17 0.97 1.22 1.11 0.19 0.95 1.30 1.06 0.52 0.89 1.26
DLBCL histology              
  9680 ref.            
  9684 1.47 < 0.001 1.21 1.79 1.52 < 0.001 1.19 1.94 1.32 0.11 0.94 1.84
Stage at diagnosis              
  I ref.            
  II 1.27 < 0.0001 1.16 1.40 1.42 < 0.0001 1.25 1.62 1.15 0.05 1.00 1.31
  III 1.51 < 0.0001 1.36 1.68 1.77 < 0.0001 1.53 2.04 1.28 < 0.01 1.10 1.50
  IV 1.86 < 0.0001 1.70 2.02 2.43 < 0.0001 2.16 2.74 1.30 < 0.0001 1.14 1.48
  unknown 1.56 < 0.0001 1.36 1.79 1.45 < 0.001 1.19 1.77 1.72 < 0.0001 1.42 2.08
NCI Comorbidity Index              
  0 ref.            
  1 1.19 < 0.0001 1.10 1.28 1.14 0.01 1.03 1.26 1.27 < 0.0001 1.13 1.42
  2 1.44 < 0.0001 1.29 1.60 1.34 < 0.0001 1.16 1.54 1.58 < 0.0001 1.35 1.85
  ≥3 1.88 < 0.0001 1.66 2.13 1.70 < 0.0001 1.44 2.01 2.16 < 0.0001 1.79 2.60
Year of Diagnosis              
  2001 ref.            
  2002 0.87 < 0.01 0.79 0.96 0.87 0.02 0.77 0.98 0.89 0.14 0.76 1.04
  2003 0.82 < 0.0001 0.74 0.90 0.76 < 0.0001 0.67 0.85 0.95 0.52 0.81 1.11
  2004 0.84 < 0.001 0.76 0.92 0.70 < 0.0001 0.62 0.79 1.16 0.07 0.99 1.35
  2005 0.80 < 0.0001 0.73 0.89 0.39 < 0.0001 0.33 0.45 1.90 < 0.0001 1.63 2.20
Percent of 25+ year olds in census tract with some college              
  0-< 25% ref.            
  25-< 50% 1.00 0.91 0.93 1.07 1.01 0.86 0.91 1.11 0.98 0.77 0.88 1.10
  ≥50% 0.90 0.61 0.60 1.35 0.81 0.46 0.45 1.43 1.00 1.00 0.57 1.76
Percent living in poverty in census tract              
  0-< 5% ref.            
  5-< 7% 1.04 0.49 0.94 1.15 1.11 0.13 0.97 1.26 0.96 0.57 0.82 1.12
  7-< 12% 1.03 0.58 0.94 1.12 1.01 0.83 0.90 1.14 1.05 0.51 0.92 1.20
  ≥12% 1.13 0.01 1.03 1.23 1.11 0.09 0.99 1.25 1.17 0.03 1.02 1.33
SEER region              
  CA ref.            
  CT 1.08 0.29 0.94 1.25 1.08 0.42 0.89 1.31 1.09 0.45 0.88 1.34
  Detroit 1.12 0.10 0.98 1.27 1.16 0.09 0.98 1.38 1.04 0.72 0.85 1.27
  HI 0.81 0.16 0.60 1.09 0.66 0.07 0.42 1.03 0.98 0.90 0.65 1.47
  IA 0.98 0.81 0.86 1.12 1.08 0.36 0.91 1.28 0.85 0.13 0.70 1.05
  NM 1.24 0.04 1.01 1.52 1.32 0.05 1.00 1.74 1.15 0.38 0.84 1.58
  Seattle 1.02 0.82 0.88 1.17 1.15 0.12 0.96 1.38 0.82 0.09 0.64 1.03
  UT 1.01 0.88 0.85 1.21 1.15 0.24 0.91 1.44 0.84 0.25 0.63 1.13
  Atlanta 0.96 0.71 0.78 1.18 0.98 0.86 0.74 1.28 0.97 0.85 0.72 1.32
  Rural GA 0.97 0.91 0.55 1.72 0.90 0.79 0.40 2.02 1.01 0.99 0.45 2.27
  KY 1.12 0.07 0.99 1.26 1.16 0.07 0.99 1.36 1.06 0.52 0.89 1.27
  LA 1.07 0.34 0.93 1.22 1.13 0.16 0.95 1.35 0.97 0.80 0.80 1.19
  NJ 1.12 0.03 1.01 1.25 1.11 0.15 0.96 1.27 1.16 0.06 1.00 1.35
Lymph node site              
  Nodal ref.            
  Extranodal 1.09 0.05 1.00 1.18 1.06 0.33 0.94 1.19 1.13 0.05 1.00 1.28
Other conditions              
  Anemia 1.31 < 0.0001 1.19 1.45 1.37 < 0.0001 1.20 1.55 1.23 0.01 1.05 1.43
  Neutropenia 1.03 0.93 0.55 1.93 0.80 0.67 0.30 2.17 1.35 0.48 0.59 3.08
  Thrombocytopenia 1.03 0.86 0.73 1.46 0.98 0.91 0.62 1.54 1.17 0.57 0.68 2.00
  Cardiovascular disease 1.26 < 0.0001 1.14 1.39 1.09 0.21 0.95 1.26 1.53 < 0.0001 1.31 1.77
  1. HR: Hazard Ratio