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Table 3 Multivariate Survival Analysis

From: Racial differences in treatment and survival in older patients with diffuse large B-cell lymphoma (DLBCL)

  

All Cause (4,188 deaths)

NHL (2,366 deaths)

Other/Unknown Cause (1,822 deaths)

  

HR

p-value

95% CI

HR

p-value

95% CI

HR

p-value

95% CI

Age

             
 

66-< 70

ref.

           
 

70-< 75

1.38

< 0.0001

1.22

1.55

1.37

< 0.001

1.16

1.61

1.38

< 0.001

1.15

1.66

 

75-< 80

1.75

< 0.0001

1.55

1.96

1.75

< 0.0001

1.50

2.05

1.72

< 0.0001

1.44

2.05

 

≥ 80

2.69

< 0.0001

2.41

3.00

2.60

< 0.0001

2.24

3.01

2.79

< 0.0001

2.36

3.29

Gender

             
 

Female

ref.

           
 

Male

1.09

< 0.01

1.03

1.16

1.05

0.22

0.97

1.14

1.14

0.01

1.04

1.25

Race

             
 

White

ref.

           
 

Black

1.24

0.01

1.06

1.46

1.16

0.19

0.93

1.45

1.35

0.01

1.06

1.71

 

Other

1.09

0.17

0.97

1.22

1.11

0.19

0.95

1.30

1.06

0.52

0.89

1.26

DLBCL histology

             
 

9680

ref.

           
 

9684

1.47

< 0.001

1.21

1.79

1.52

< 0.001

1.19

1.94

1.32

0.11

0.94

1.84

Stage at diagnosis

             
 

I

ref.

           
 

II

1.27

< 0.0001

1.16

1.40

1.42

< 0.0001

1.25

1.62

1.15

0.05

1.00

1.31

 

III

1.51

< 0.0001

1.36

1.68

1.77

< 0.0001

1.53

2.04

1.28

< 0.01

1.10

1.50

 

IV

1.86

< 0.0001

1.70

2.02

2.43

< 0.0001

2.16

2.74

1.30

< 0.0001

1.14

1.48

 

unknown

1.56

< 0.0001

1.36

1.79

1.45

< 0.001

1.19

1.77

1.72

< 0.0001

1.42

2.08

NCI Comorbidity Index

             
 

0

ref.

           
 

1

1.19

< 0.0001

1.10

1.28

1.14

0.01

1.03

1.26

1.27

< 0.0001

1.13

1.42

 

2

1.44

< 0.0001

1.29

1.60

1.34

< 0.0001

1.16

1.54

1.58

< 0.0001

1.35

1.85

 

≥3

1.88

< 0.0001

1.66

2.13

1.70

< 0.0001

1.44

2.01

2.16

< 0.0001

1.79

2.60

Year of Diagnosis

             
 

2001

ref.

           
 

2002

0.87

< 0.01

0.79

0.96

0.87

0.02

0.77

0.98

0.89

0.14

0.76

1.04

 

2003

0.82

< 0.0001

0.74

0.90

0.76

< 0.0001

0.67

0.85

0.95

0.52

0.81

1.11

 

2004

0.84

< 0.001

0.76

0.92

0.70

< 0.0001

0.62

0.79

1.16

0.07

0.99

1.35

 

2005

0.80

< 0.0001

0.73

0.89

0.39

< 0.0001

0.33

0.45

1.90

< 0.0001

1.63

2.20

Percent of 25+ year olds in census tract with some college

             
 

0-< 25%

ref.

           
 

25-< 50%

1.00

0.91

0.93

1.07

1.01

0.86

0.91

1.11

0.98

0.77

0.88

1.10

 

≥50%

0.90

0.61

0.60

1.35

0.81

0.46

0.45

1.43

1.00

1.00

0.57

1.76

Percent living in poverty in census tract

             
 

0-< 5%

ref.

           
 

5-< 7%

1.04

0.49

0.94

1.15

1.11

0.13

0.97

1.26

0.96

0.57

0.82

1.12

 

7-< 12%

1.03

0.58

0.94

1.12

1.01

0.83

0.90

1.14

1.05

0.51

0.92

1.20

 

≥12%

1.13

0.01

1.03

1.23

1.11

0.09

0.99

1.25

1.17

0.03

1.02

1.33

SEER region

             
 

CA

ref.

           
 

CT

1.08

0.29

0.94

1.25

1.08

0.42

0.89

1.31

1.09

0.45

0.88

1.34

 

Detroit

1.12

0.10

0.98

1.27

1.16

0.09

0.98

1.38

1.04

0.72

0.85

1.27

 

HI

0.81

0.16

0.60

1.09

0.66

0.07

0.42

1.03

0.98

0.90

0.65

1.47

 

IA

0.98

0.81

0.86

1.12

1.08

0.36

0.91

1.28

0.85

0.13

0.70

1.05

 

NM

1.24

0.04

1.01

1.52

1.32

0.05

1.00

1.74

1.15

0.38

0.84

1.58

 

Seattle

1.02

0.82

0.88

1.17

1.15

0.12

0.96

1.38

0.82

0.09

0.64

1.03

 

UT

1.01

0.88

0.85

1.21

1.15

0.24

0.91

1.44

0.84

0.25

0.63

1.13

 

Atlanta

0.96

0.71

0.78

1.18

0.98

0.86

0.74

1.28

0.97

0.85

0.72

1.32

 

Rural GA

0.97

0.91

0.55

1.72

0.90

0.79

0.40

2.02

1.01

0.99

0.45

2.27

 

KY

1.12

0.07

0.99

1.26

1.16

0.07

0.99

1.36

1.06

0.52

0.89

1.27

 

LA

1.07

0.34

0.93

1.22

1.13

0.16

0.95

1.35

0.97

0.80

0.80

1.19

 

NJ

1.12

0.03

1.01

1.25

1.11

0.15

0.96

1.27

1.16

0.06

1.00

1.35

Lymph node site

             
 

Nodal

ref.

           
 

Extranodal

1.09

0.05

1.00

1.18

1.06

0.33

0.94

1.19

1.13

0.05

1.00

1.28

Other conditions

             
 

Anemia

1.31

< 0.0001

1.19

1.45

1.37

< 0.0001

1.20

1.55

1.23

0.01

1.05

1.43

 

Neutropenia

1.03

0.93

0.55

1.93

0.80

0.67

0.30

2.17

1.35

0.48

0.59

3.08

 

Thrombocytopenia

1.03

0.86

0.73

1.46

0.98

0.91

0.62

1.54

1.17

0.57

0.68

2.00

 

Cardiovascular disease

1.26

< 0.0001

1.14

1.39

1.09

0.21

0.95

1.26

1.53

< 0.0001

1.31

1.77

  1. HR: Hazard Ratio
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