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Table 2 Multivariate Analysis of Treatment

From: Racial differences in treatment and survival in older patients with diffuse large B-cell lymphoma (DLBCL)

   Time to Treatment -
Overall
Time to Treatment -
Stage I & II
Time to Treatment -
Stage III & IV
Treatment within 180 days
   HR p-value 95% CI HR p-value 95% CI HR p-value 95% CI OR p-value 95% CI
Age                  
  64-< 70 ref.                
  70-< 75 1.00 0.91 0.91 1.08 0.90 0.07 0.79 1.01 1.10 0.16 0.96 1.24 0.73 0.01 0.59 0.91
  75-< 80 0.95 0.20 0.87 1.03 0.91 0.12 0.81 1.03 0.99 0.86 0.87 1.12 0.59 < 0.0001 0.48 0.73
  ≥ 80 0.78 < 0.0001 0.72 0.84 0.69 < 0.0001 0.62 0.77 0.89 0.07 0.79 1.01 0.38 < 0.0001 0.31 0.46
Gender                  
  Female ref.                
  Male 0.99 0.70 0.94 1.04 1.01 0.83 0.94 1.09 0.97 0.42 0.89 1.05 0.85 0.01 0.76 0.95
Race                  
  White ref                
  Black 0.77 < 0.001 0.66 0.89 0.76 0.01 0.61 0.95 0.76 0.02 0.60 0.96 0.63 < 0.01 0.47 0.85
  other 1.01 0.78 0.92 1.12 1.06 0.42 0.92 1.21 0.95 0.57 0.81 1.12 0.99 0.89 0.79 1.22
Histology                  
  9680 ref                
  9684 0.86 0.10 0.71 1.03 0.70 0.01 0.53 0.92 1.16 0.27 0.89 1.50 0.66 0.03 0.45 0.95
Stage at diagnosis                  
  I ref                
  II 1.20 < 0.0001 1.11 1.29 1.21 < 0.0001 1.12 1.30      1.32 < 0.01 1.11 1.58
  III 1.27 < 0.0001 1.17 1.38          1.04 0.71 0.86 1.26
  IV 1.23 < 0.0001 1.14 1.32      0.93 0.37 0.80 1.08 0.91 0.22 0.78 1.06
  unknown 0.85 0.01 0.75 0.96          0.56 < 0.0001 0.44 0.71
NCI Comorbidity Index                  
  0 ref                
  1 1.05 0.15 0.98 1.12 1.03 0.53 0.94 1.13 1.09 0.07 0.99 1.20 1.00 0.95 0.86 1.15
  2 1.03 0.51 0.94 1.14 1.03 0.64 0.90 1.18 1.09 0.24 0.94 1.26 0.87 0.19 0.71 1.07
  ≥3 0.93 0.25 0.82 1.05 1.04 0.64 0.88 1.24 0.89 0.25 0.73 1.09 0.56 < 0.0001 0.44 0.71
Year of diagnosis                  
  2001 ref                
  2002 0.99 0.84 0.91 1.08 0.95 0.35 0.84 1.06 1.08 0.25 0.95 1.23 0.95 0.57 0.79 1.14
  2003 1.04 0.37 0.96 1.13 1.00 0.99 0.89 1.12 1.10 0.14 0.97 1.25 1.18 0.08 0.98 1.42
  2004 1.03 0.53 0.95 1.12 1.00 0.98 0.89 1.12 1.04 0.51 0.92 1.19 1.17 0.09 0.98 1.41
  2005 0.99 0.89 0.91 1.08 0.93 0.26 0.83 1.05 1.08 0.24 0.95 1.22 1.00 0.99 0.83 1.20
Percent of 25+ year olds in census tract with some college                  
  0-< 25% ref                
  25-< 50% 0.95 0.11 0.89 1.01 0.91 0.03 0.83 0.99 0.96 0.39 0.87 1.06 0.92 0.25 0.80 1.06
  ≥50% 0.84 0.34 0.59 1.20 0.87 0.61 0.52 1.46 0.87 0.68 0.45 1.70 0.50 0.04 0.26 0.98
Percent living in poverty in census tract                  
  0-< 5% ref                
  5-< 7% 0.92 0.04 0.84 1.00 0.94 0.31 0.84 1.06 0.92 0.18 0.81 1.04 0.87 0.15 0.73 1.05
  7-< 12% 0.97 0.36 0.90 1.04 0.95 0.32 0.86 1.05 0.97 0.54 0.86 1.08 0.95 0.51 0.80 1.12
  ≥12% 0.90 0.01 0.83 0.97 0.92 0.10 0.82 1.02 0.89 0.04 0.79 1.00 0.82 0.02 0.70 0.97
SEER region                  
  CA ref                
  CT 1.05 0.40 0.93 1.19 1.01 0.87 0.86 1.20 1.10 0.33 0.91 1.32 1.14 0.34 0.87 1.50
  Detroit 0.99 0.84 0.89 1.10 0.96 0.57 0.82 1.12 1.09 0.32 0.92 1.28 1.07 0.61 0.83 1.37
  HI 0.95 0.65 0.74 1.21 0.90 0.54 0.65 1.25 1.01 0.95 0.68 1.50 1.07 0.81 0.62 1.85
  IA 1.16 0.01 1.05 1.29 1.31 < 0.001 1.13 1.51 1.04 0.67 0.88 1.22 1.44 < 0.01 1.12 1.86
  NM 1.17 0.09 0.98 1.39 1.23 0.10 0.96 1.58 1.11 0.47 0.84 1.47 0.92 0.68 0.64 1.35
  Seattle 1.01 0.93 0.89 1.13 1.08 0.40 0.91 1.28 0.97 0.72 0.82 1.15 1.29 0.07 0.98 1.70
  UT 0.93 0.32 0.80 1.08 0.91 0.34 0.75 1.11 0.99 0.90 0.79 1.24 0.90 0.52 0.65 1.24
  Atlanta 1.08 0.38 0.91 1.27 1.05 0.71 0.82 1.35 1.09 0.47 0.86 1.40 1.16 0.45 0.79 1.69
  Rural GA 1.04 0.89 0.62 1.73 0.76 0.47 0.36 1.61 1.32 0.54 0.54 3.22 0.84 0.72 0.31 2.27
  KY 0.95 0.37 0.86 1.06 1.00 0.95 0.87 1.16 0.96 0.58 0.81 1.13 0.91 0.42 0.73 1.14
  LA 1.06 0.33 0.95 1.18 1.01 0.88 0.87 1.18 1.18 0.06 0.99 1.41 1.09 0.51 0.85 1.39
  NJ 1.05 0.32 0.96 1.14 1.05 0.48 0.93 1.18 1.05 0.51 0.91 1.20 0.96 0.65 0.79 1.16
Lymph node site                  
  Nodal ref.                
  Extra-nodal 0.90 < 0.01 0.85 0.97 0.90 < 0.01 0.83 0.96 0.95 0.55 0.81 1.12 0.88 0.09 0.75 1.02
Other conditions                  
  Anemia 1.04 0.42 0.95 1.14 1.04 0.60 0.90 1.19 1.02 0.83 0.88 1.17 0.67 < 0.0001 0.55 0.80
  Neutropenia 1.03 0.93 0.56 1.87 0.47 0.19 0.15 1.46 1.51 0.38 0.61 3.75 0.54 0.28 0.18 1.65
  Thrombocytopenia 1.35 0.07 0.97 1.88 1.88 0.02 1.12 3.17 0.97 0.88 0.61 1.54 0.51 0.04 0.27 0.97
  Cardiovascular disease 0.99 0.77 0.89 1.09 1.01 0.86 0.88 1.16 0.93 0.33 0.79 1.08 0.93 0.49 0.76 1.14
  1. HR: Hazard Ratio
  2. OR: Odds Ratio