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Table 3 Relative survival according to patient and tumour characteristics: Univariate and multivariate analyses

From: Population-based study of ovarian cancer in Côte d'Or: prognostic factors and trends in relative survival rates over the last 20 years

    Relative survival   Univariate analysis N = 748 Multivariate analysis N = 722
Variables Patients at risk Number of deaths 1-year RS (CI) 3-year RS (CI) 5-year RS (CI) HR 95% CI P value HR 95% CI P value
Age         < 0.0001    0.003
   < 50 154 79 89 (82.7-93.0) 68 (60.4-75.3) 58 (50.0-65.9) 1    1   
   50-70 359 243 84 (79.6-87.4) 55 (50.8-60.6) 43 (37.8-48.5) 1.51 1.16-1.95 < 0.0001 1.22 0.94-1.59 0.12
   ≥ 70 235 194 70 (63.4-76.0) 42 (35.2-49.2) 32 (24.9-38.7) 2.23 1.78-2.93 0.001 1.60 1.21-2.12 0.0009
Stage at diagnosis         < 0.0001    < 0.0001
   I 186 58 98 (93.9-99.3) 89 (82.7-93.1) 85 (78.1-90.0) 1    1   
   II 60 44 82 (68.4-89.8) 60.3 (45.9-72.1) 48 (34.5-61.0) 4.51 2.69-7.57 < 0.0001 4.43 2.63-7.46 < 0.0001
   III 387 320 78 (73.5-82.0) 44 (38.8-49.1) 29 (24.0-33.6) 7.99 5.34-11.96 < 0.0001 8.80 5.81-13.34 < 0.0001
   IV 90 78 62 (50.5-71.1) 28 (18.6-37.8) 14 (6.7-22.7) 12.82 8.18-20.08 < 0.0001 13.07 8.26-20.66 < 0.0001
   Unknown 25 16          
Histological type         0.0001    0.010
   Serous 433 309 84 (80.4-87.7) 56(50.8-60.7) 41 (36.3-46.3) 1    1   
   Mucinous- Endometrioid 167 105 82(75.3-87.4) 56 (48.1-63.7) 49 (40.8-56.9) 0.74 0.58-0.96 0.022 1.23 0.95-1.58 0.11
   Other epithelial 91 73 65 (54.4-74.4) 40 (29.2-49.8) 31 (21.0-41.2) 1.37 1.04-1.82 0.023 1.62 1.22-2.16 0.0008
   Non epithelial 57 29 78 (63.6-87.5) 67 (50.6-78.6) 63 (46.8-75.1) 0.53 0.33-0.84 0.007 1.19 0.72-1.96 0.47
Period of diagnosis         0.0004    0.0001
   1982-1989 221 159 82 (75.8-86.6) 49 (42.0-56.0) 41 (34.2-48.2) 1    1   
   1990-1997 255 191 74 (68.1-79.3) 50 (43.4-56.3) 39 (32.8-45.6) 1.07 0.86-1.34 0.5217 0.96 0.77-1.21 0.79
   1998-2005 272 166 87 (82.2-90.8) 64 (57.2-69.3) 49 (42.5-55.5) 0.67 0.52-0.87 0.002 0.52 0.40-0.67 < 0.0001
Place of residence            
   Rural 335 242 79 (74.0-83.2) 40 (34.7-46.0) 40 (34.7-46.0) 1    1   
   Urban 412 273 83 (78.6-86.4) 46 (40.6-51.1) 46 (40.6-51.1) 0.81 0.67-0.99 0.04 0.82 0.67-0.99 0.04
   Unknown 1 1          
Menopause            
   Yes 450 346 78 (74.1-82.2) 49 (43.8-53.6) 36 (31.4-41.0) 1      
   No 138 72 88 (81.0-92.5) 70 (60.8-76.7) 60 (50.8-67.7) 1.93 1.48-2.51 < 0.0001    
   Unknown 160 98 83 (75.6-88.0) 58 (49.4-65.5) 49 (40.2-57.0)       
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