Table 2 Function annotation from IPA for 23 recurrently enriched genes identified by GSEA^a

Proliferation of normal cells

1.35E-15

ADM, CCND1, CD44, CDH2, FGF2, FN1, GUCY1A3, HOXA10, IL6, IL8, IL12A, ITGB3, MMP9, NCAM1, PLAU, PTGS2, S1PR1, SPP1, SPTBN1, TGFBR2, TNC, VCAM1, VEGFA

23

Migration of normal cells

1.77E-17

ADM, CCND1, CD44, CDH2, FGF2, FN1, GUCY1A3, IL6, IL8, IL12A, ITGB3, MMP9, NCAM1, PLAU, PTGER4, PTGS2, S1PR1, SPP1, TGFBR2, TNC, VCAM1, VEGFA

22

Malignant tumor

3.18E-10

CCND1, CD44, CDH2, FGF2, FN1, IL6, IL8, IL12A, ITGB3, MMP9, NCAM1, PLAU, PTGER4, PTGS2, S1PR1, SPP1, SPTBN1, TGFBR2, TNC, VCAM1, VEGFA

21

Apoptosis

9.50E-10

ADM, CCND1, CD44, CDH2, FGF2, FN1, IL6, IL8, IL12A, ITGB3, MMP9, NCAM1, PLAU, PTGER4, PTGS2, S1PR1, SLC2A3, SPP1, TGFBR2, TNC, VEGFA

21

Development of blood vessel

3.09E-14

CCND1, CDH2, FGF2, FN1, IL6, IL8, IL12A, ITGB3, MMP9, PLAU, PTGER4, PTGS2, S1PR1, TGFBR2, VCAM1, VEGFA

16

Angiogenesis

3.09E-14

CCND1, FGF2, FN1, IL6, IL8, IL12A, ITGB3, MMP9, PLAU, PTGER4, PTGS2, S1PR1, TGFBR2, VCAM1, VEGFA

15

Adhesion of normal cells

2.82E-14

CCND1, CD44, CDH2, FGF2, FN1, IL6, IL8, ITGB3, NCAM1, PLAU, SPP1, TGFBR2, TNC, VCAM1, VEGFA

15

Proliferation of blood cells

3.62E-09

CD44, FGF2, FN1, HOXA10, IL6, IL8, IL12A, ITGB3, MMP9, PTGS2, SPP1, TGFBR2, VCAM1

13

Metastasis

1.11E-12

CD44, CDH2, FGF2, IL6, IL12A, ITGB3, MMP9, NCAM1, PTGS2, SPP1, TGFBR2, VEGFA

12

Inflammatory response

7.51E-09

CCND1, CD44, FN1, IL6, IL8, MMP9, PLAU, PTGER4, PTGS2, S1PR1, SPP1, VEGFA

12

Inflammation

1.01E-09

CD44, FGF2, IL6, IL8, IL12A, MMP9, PTGER4, PTGS2, SPP1, TGFBR2, VEGFA

11

Infiltration of cells

3.00E-10

CD44, FN1, IL6, IL8, IL12A, ITGB3, MMP9, SPP1, VCAM1, VEGFA

10