Table 8 Identification of canine genes in the expression profile of metastatic CMT homologous or similar to the 70-gene prognostic signature for human breast cancer
Human genes of the 70 prognostic gene profile (van't Veer et al.) | Homologous genes expressed in metastatic canine tumors | Gene family members expressed in canine tumors |
|---|---|---|
Homologous genes present on canine gene array | Â | Â |
   AP2B1 | AP2B1 | - |
   CCNE2 | - | CCNE1 |
   CDC42BPA | - | - |
   CENPA | CENPA | - |
   COL4A2 |  | COL2, 16 |
   DCK | DCK | - |
   DIAPH3 | DIAPH3 | - |
   ECT2 | ECT2 | - |
   EGLN1 | - | - |
   ESM1 | ESM1 | - |
   EXT1 | - | - |
   FGF18 | - | - |
   FLT1 | - | - |
   GMPS | - | GMPS |
   GNAZ | - | - |
   HRASLS | - | - |
   IGFBP5 | - | - |
   LPCAT1 | LPCAT1 | - |
   MCM6 | MCM6 | - |
   MELK | MELK | - |
   MMP9 | - | MMP11 |
   MS4A7 | - | - |
   NDC80 | NDC80 | - |
   ORC6L | ORC6L | - |
   OXCT | - | - |
   PECI | - | - |
   PRC1 | PRC1 |  |
   RAB6B | - | RAB10, 7L1, EPK |
   RFC4 | - | RFC2, 3 |
   SCUBE2 | - | - |
   SLC2A3 | - | - |
   STK32 | - | STK3, 4, 11 |
   TGFB3 | - | - |
   UCHL5 | - | UCHL3 |
   ALDH4 | - | ALDH16 |
   FAM2A | - | FAM13B |
   NMU | - | NMB |