Skip to main content

Table 1 Associations between TFPI- 2 promoter methylation and clinicopathological indices of NPC

From: TFPI-2 is a putative tumor suppressor gene frequently inactivated by promoter hypermethylation in nasopharyngeal carcinoma

  

Promoter methylation status

 
 

Number of patients

Methylated

Unmethylated

Statistic significance

Age

    

   < 60

58

52(89.7%)

6

NS

   ≥ 60

12

10(83.3%)

2

 

Gender

    

   Male

48

44(91.7%)

4

NS

   Female

22

18(81.8%)

4

 

Stage*

    

   I-II

28

24(85.7%)

4

NS

   III-IV

42

38(90.5%)

4

 

Histological subtype

    

   Keratinizing squamous cell carcinoma

8

6(75%)

2

NS

   Non-keratinizing carcinoma

62

56(90.3%)

6

 

Lymph node metastasis

    

   Presence

58

50(86.2%)

8

NS

   Absence

12

12(100%)

0

 
  1. *: Staging according to International Union Against Cancer (UICC).
  2. NS: not statistically significant