Figure 7
Suppression of miR-31 decreased cell migration. (A) Boyden chamber with 8 μm pore polycarbonate membrane was used for the migration assay. The chamber was stained and analyzed by photography, the stained cells were migratory cells in the lower chamber. (B) The migratroy cells decreased nearly 50% in both HCT-116p53+/+ and HCT-116p53-/- cells when they were normalized to negative control transfected cells (p = 0.040 and 0.001).