|
Astrocytic tumor samples Grade and Sample ID
|
Expression of Cyclin D2 in tumor samples
|
Methylation by MSP in Cyclin D2 promoter
|
Methylation by MCA-Meth in Cyclin D2 promoter
|
Methylation by both techniques in Cyclin D2 promoter
|
No hypermethylation in Cyclin D2 promoter
|
Expression of PTCH1 in tumor samples
|
Methylation of PTCH1 promoter by MCA-Meth
|
|---|
|
GBM(3)
|
-
|
√
|
√
|
√
| |
-
|
√
|
|
AIII(4)
|
++
| | | |
√
|
+
| |
|
GBM(5)
|
-
| | | |
√
|
+/-
| |
|
GBM(6)
|
-
|
√
| | | |
+/-
| |
|
AIII(7)
|
+
| | | |
√
|
+/-
| |
|
GBM(8)
|
-
|
√
| | | |
++
| |
|
GBM(9)
|
+
| | | |
√
|
-
| |
|
AIII(10)
|
-
|
√
| | | |
+/-
| |
|
GBM(11)
|
++
| | | |
√
|
+/-
| |
|
GBM(12)
|
+
| | | |
√
|
+
| |
|
GBM(13)
|
-
|
√
|
√
|
√
| |
+
|
√
|
|
AIII(14)
|
++
| |
√
| | |
-
| |
|
GBM(15)
|
-
|
√
| | | |
+/-
| |
|
AIII(16)
|
++
|
√
| | | |
+/-
| |
|
GBM(17)
|
-
| |
√
| | |
++
| |
|
GBM(18)
|
-
|
√
|
√
|
√
| |
+
| |
|
AIII(19)
|
+
| |
√
| | |
+
| |
|
AII(20)
|
+
| |
√
| | |
+
| |
|
AIII(21)
|
-
|
√
| | | |
-
|
√
|
|
GBM(22)
|
-
| |
√
| | |
-
| |
|
GBM(23)
|
-
| |
√
| | |
+
| |
|
GBM(24)
|
-
|
√
|
√
|
√
| |
+
| |
|
AI(25)
|
ND
| | | |
√
|
ND
| |
|
GBM(26)
|
ND
| | | |
√
|
ND
| |
|
GBM(27)
|
ND
| | | |
√
|
ND
| |
|
GBM(28)
|
ND
| | | |
√
|
ND
| |
|
GBM(29)
|
ND
| | | |
√
|
ND
| |
|
GBM(30)
|
+
|
√
| | | |
+
| |
|
GBM(31)
|
ND
| | | |
√
|
ND
| |
|
GBM(32)
|
ND
| | | |
√
|
ND
| |
|
AI(34)
|
ND
| | | |
√
|
ND
| |
|
AIII(35)
|
ND
| | | |
√
|
ND
| |
|
GBM(36)
|
ND
| | | |
√
|
ND
| |
|
GBM(41)
|
ND
| | | |
√
|
ND
| |
|
GBM(43)
|
+
|
√
| | | |
-
| |
|
GBM(44)
|
ND
| | | |
√
|
ND
| |
|
GBM(45)
|
ND
| | | |
√
|
ND
| |
|
GBM(46)
|
ND
| | | |
√
|
ND
| |
|
GBM(47)
|
ND
| | | |
√
|
ND
| |
|
GBM(48)
|
ND
|
√
| | | |
ND
| |
|
GBM(49)
|
ND
|
√
| | | |
ND
| |
|
AII(50)
|
++
| | | |
√
|
-
| |
|
GBM(51)
|
-
|
√
| | | |
-
| |
|
GBM(52)
|
++
| | | |
√
|
+
| |
- -:no expression; +/-: low expression; +: expression; ++: high expression; √: yes; nd: not determined
