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Table 2 Promoter methylation and expression correlation of Cyclin D2 and PTCH1 gene in medulloblastoma samples

From: Regulation of sonic hedgehog-GLI1 downstream target genes PTCH1, Cyclin D2, Plakoglobin, PAX6 and NKX2.2 and their epigenetic status in medulloblastoma and astrocytoma

MB samples ID Patients' Date of Birth (D/M/Y) Sex Expression of Cyclin D2 in primary tumor samples Promoter methylation by MCA-Meth in Cyclin D2 Promoter methylation by MSP in Cyclin D2 No Promoter hypermethylation in Cyclin D2 Expression of PTCH1 in primary tumor samples Promoter hypermethylation in PTCH1 by MCA-Meth of PTCH1
p3 5/18/1969 M ++ U U - U + M
p4 3/9/1987 M - U U + M   + U
p7 11/27/1987 M ++ U U + U
p10 4/15/1971 M ++ U U nd U
p11 4/30/1997 F + U U + M   - U + M
p13 8/21/1995 F + U U + M   nd U
p14 9/9/1991 F ++ U U + U
p17 11/30/1988 M ++ U U + U
p20 11/22/1978 M ++ U U + U
p21 11/15/1987 M ++ U U + U
p29 3/9/1974 M ++ U U nd U
p30 6/24/1991 M ++ U U nd nd
p23 8/15/1984 F nd nd nd nd nd nd
p52 10/5/1991 M nd nd nd nd nd nd
  1. MB: medulloblastoma; -: no expression; +: expression; ++: high expression; √: yes