Table 2 Promoter methylation and expression correlation of Cyclin D2 and PTCH1 gene in medulloblastoma samples
MB samples ID | Patients' Date of Birth (D/M/Y) | Sex | Expression of Cyclin D2 in primary tumor samples | Promoter methylation by MCA-Meth in Cyclin D2 | Promoter methylation by MSP in Cyclin D2 | No Promoter hypermethylation in Cyclin D2 | Expression of PTCH1 in primary tumor samples | Promoter hypermethylation in PTCH1 by MCA-Meth of PTCH1 |
|---|---|---|---|---|---|---|---|---|
p3 | 5/18/1969 | M | ++ | U | U | √ | - | U + M |
p4 | 3/9/1987 | M | - | U | U + M | Â | + | U |
p7 | 11/27/1987 | M | ++ | U | U | √ | + | U |
p10 | 4/15/1971 | M | ++ | U | U | √ | nd | U |
p11 | 4/30/1997 | F | + | U | U + M | Â | - | U + M |
p13 | 8/21/1995 | F | + | U | U + M | Â | nd | U |
p14 | 9/9/1991 | F | ++ | U | U | √ | + | U |
p17 | 11/30/1988 | M | ++ | U | U | √ | + | U |
p20 | 11/22/1978 | M | ++ | U | U | √ | + | U |
p21 | 11/15/1987 | M | ++ | U | U | √ | + | U |
p29 | 3/9/1974 | M | ++ | U | U | √ | nd | U |
p30 | 6/24/1991 | M | ++ | U | U | √ | nd | nd |
p23 | 8/15/1984 | F | nd | nd | nd | nd | nd | nd |
p52 | 10/5/1991 | M | nd | nd | nd | nd | nd | nd |