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Table 2 Promoter methylation and expression correlation of Cyclin D2 and PTCH1 gene in medulloblastoma samples

From: Regulation of sonic hedgehog-GLI1 downstream target genes PTCH1, Cyclin D2, Plakoglobin, PAX6 and NKX2.2 and their epigenetic status in medulloblastoma and astrocytoma

MB samples ID

Patients' Date of Birth (D/M/Y)

Sex

Expression of Cyclin D2 in primary tumor samples

Promoter methylation by MCA-Meth in Cyclin D2

Promoter methylation by MSP in Cyclin D2

No Promoter hypermethylation in Cyclin D2

Expression of PTCH1 in primary tumor samples

Promoter hypermethylation in PTCH1 by MCA-Meth of PTCH1

p3

5/18/1969

M

++

U

U

-

U + M

p4

3/9/1987

M

-

U

U + M

 

+

U

p7

11/27/1987

M

++

U

U

+

U

p10

4/15/1971

M

++

U

U

nd

U

p11

4/30/1997

F

+

U

U + M

 

-

U + M

p13

8/21/1995

F

+

U

U + M

 

nd

U

p14

9/9/1991

F

++

U

U

+

U

p17

11/30/1988

M

++

U

U

+

U

p20

11/22/1978

M

++

U

U

+

U

p21

11/15/1987

M

++

U

U

+

U

p29

3/9/1974

M

++

U

U

nd

U

p30

6/24/1991

M

++

U

U

nd

nd

p23

8/15/1984

F

nd

nd

nd

nd

nd

nd

p52

10/5/1991

M

nd

nd

nd

nd

nd

nd

  1. MB: medulloblastoma; -: no expression; +: expression; ++: high expression; √: yes