Table 1 Promoter methylation and expression correlation of Cyclin D2 and PTCH1 gene in medulloblastoma cell lines
Cell lines | Cyclin D2 expression | Cyclin D2 promoter hypermethylation by MCA-Meth | Cyclin D2 Hypermethylation by MSP | Cyclin D2 Hypermethylation by both methods | No Hyper Methylation in Cyclin D2 Promoter | PTCH1 Expression in medulloblastoma cell lines | PTCH1 promoter Hypermethylation by MCA-MSP method |
|---|---|---|---|---|---|---|---|
TE671 | ++ | U | M | Â | Â | ++ | U |
PFSK-1 | ++ | M | M | √ |  | ++ | U |
Daoy | ++ | U | U+M | Â | Â | ++ | U |
TE671c2 | ++ | U | U+M | Â | Â | + | U |
D283 | ++ | U | U + M | Â | Â | + | U+M |
SK-PN-DW | + | U+M | M | √ |  | + | U |