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Table 1 Promoter methylation and expression correlation of Cyclin D2 and PTCH1 gene in medulloblastoma cell lines

From: Regulation of sonic hedgehog-GLI1 downstream target genes PTCH1, Cyclin D2, Plakoglobin, PAX6 and NKX2.2 and their epigenetic status in medulloblastoma and astrocytoma

Cell lines Cyclin D2 expression Cyclin D2 promoter hypermethylation by MCA-Meth Cyclin D2 Hypermethylation by MSP Cyclin D2 Hypermethylation by both methods No Hyper Methylation in Cyclin D2 Promoter PTCH1 Expression in medulloblastoma cell lines PTCH1 promoter Hypermethylation by MCA-MSP method
TE671 ++ U M    ++ U
PFSK-1 ++ M M   ++ U
Daoy ++ U U+M    ++ U
TE671c2 ++ U U+M    + U
D283 ++ U U + M    + U+M
SK-PN-DW + U+M M   + U
  1. -: no expression; +: expression; ++: high expression; √: yes