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Figure 3 | BMC Cancer

Figure 3

From: Columnar cell lesions of the canine mammary gland: pathological features and immunophenotypic analysis

Figure 3

Canine mammary biopsies with flat epithelial atypia (FEA) H&E stain. 3A Low-power view; terminal duct lobular unit shows larger acini with cellular atypia, prominent apical cytoplasmic snouts, to be lined by >2 cell layers. 200×; 3B Higher power view; the columnar epithelial cells (> 2 layers) lining the acini with intraluminal secretions show cytological atypia, characterized by apical cytoplasmic snouts and enlarged, uniform nuclei; the nuclear/cytoplasmic ratio is increased. Nucleoli are evident in some of the nuclei, 600×.

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