From: Randomised trial of proton vs. carbon ion radiation therapy in patients with chordoma of the skull base, clinical phase III study HIT-1-Study
Low-risk
High-risk
Age > 30 years
Age ≤ 30 years
Male chordoma
Female chordoma
No OAR compression
Compression of OAR
Primary tumour
Recurrent tumor
Tumour size < 70 ml
Tumour size > 70 ml