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Table 4 Expression of VLDLR II in different histological types of lung cancer

From: Up-regulated expression of type II very low density lipoprotein receptor correlates with cancer metastasis and has a potential link to β-catenin in different cancers

 

IHC

(Histoscore of VLDLR II)

Western blot

(Ratio of VLDLR II/β-actin)

 

N

mean

SD.

P

N

Mean

SD.

P

ADCA

10

   

18

   

   Normal tissue

10

0.71

0.12

0.034*

18

0.60

0.18

0.048*

   Cancer tissue

10

1.29

0.71

 

18

0.70

0.25

 

SQCA

13

   

24

   

   Normal tissue

13

0.68

0.68

0.651

24

0.54

0.16

0.602

   Cancer tissue

13

0.75

0.58

 

24

0.56

0.18

 

SCLC

1

   

6

   

   Normal tissue

1

0.4

--

--

6

0.56

0.20

0.554

   Cancer tissue

1

0.6

  

6

0.59

0.30

 

A-SCA

    

3

   

   Normal tissue

--

--

--

--

3

0.49

0.09

0.118

   Cancer tissue

--

--

  

3

0.58

0.07

 
  1. ADCA indicates adenocarcinoma; SQCA, squamous cell carcinoma; SCLC, small cell carcinoma; A-SCA, adeno-squamous carcinoma. Statistical analyses were performed by Paired Students' t test (2-tailed).
  2. * P < 0.05 is considered significant.