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Table 3 Correlation between VLDLR II expression and clinical features in 46 Breast cancer patients

From: Up-regulated expression of type II very low density lipoprotein receptor correlates with cancer metastasis and has a potential link to β-catenin in different cancers

Parameters Number VLDLR II fold P
Age at diagnosis    
≥ 50 years 29 1.30 ± 0.44 0.820
< 50 years 17 1.28 ± 0.40  
Body weight    
≥ 50 kg 19 1.38 ± 0.39 0.080
< 50 kg 27 1.21 ± 0.43  
TC    
> 5.20 mmol/L 7 1.09 ± 0.34 0.178
≤ 5.20 mmol/L 39 1.31 ± 0.42  
TG    
> 1.70 mmol/L 13 1.15 ± 0.28 0.360
≤ 1.70 mmol/L 33 1.33 ± 0.45  
Histological grade    
Well to moderately differentiated 28 1.18 ± 0.36 0.043*
Poorly differentiated 18 1.43 ± 0.45  
Tumor size    
≥ 2 cm 21 1.34 ± 0.47 0.442
< 2 cm 25 1.22 ± 0.37  
Lymph node metastasis    
Negative 15 1.14 ± 0.15 0.003*
Positive 31 1.43 ± 0.45  
Distant metastasis    
Negative 32 1.16 ± 0.30 0.007*
Positive 14 1.52 ± 0.41  
TNM stage    
Stage I-II 24 1.14 ± 0.31 0.027*
Stage III-IV 22 1.41 ± 0.47  
  1. Folds (VLDLR II protein in tumor/in normal) in mean ± SD. VLDLR II measured by Western blot. TC, total cholesterol (normal range: ≤ 5.20 mmol/L); TG, triglycerides (normal range: ≤ 1.70 mmol/L). Statistical analyses were performed by Mann-Whitney test.
  2. * P < 0.05 is considered significan