From: Prioritizing genes associated with prostate cancer development
Function and gene categorya | No. of genesb | Absolute Z score (SE) | ttest | Degrees of freedom | p value |
---|---|---|---|---|---|
TGF-β signaling | 86 | 2.58 (0.34) | 4.05 | 15,770 | 0.00005 |
Integrins | 30 | 2.47 (0.35) | 3.82 | 15,773 | 0.0001 |
AR signaling pathway | 32 | 2.22 (0.34) | 2.9 | 15,780 | 0.004 |
Components of EC matrix | 64 | 2.11 (0.25) | 3.41 | 15,812 | 0.0006 |
Cell adhesion | 406 | 2.08 (0.09) | 7.99 | 16,154 | <10E-6 |
Wnt signaling pathway | 29 | 2.06 (0.27) | 2.13 | 15,777 | 0.03 |
Bone development | 56 | 1.99 (0.24) | 2.53 | 15,804 | 0.01 |
Collagens | 40 | 1.76 (0.28) | 1.07 | 15,759 | 0.28 |
Cadherins | 23 | 1.35 (0.19) | 0.61 | 15,767 | 0.54 |