Skip to main content
Figure 1 | BMC Cancer

Figure 1

From: Potential pitfalls in MitoChip detected tumor-specific somatic mutations: a call for caution when interpreting patient data

Figure 1

The mtDNA phylogenetic tree constructed on tumor cases: The Head and Neck Squamous Cell Carcinoma-HNSCC patients #1736, #1836, #2455, #2714, and #2828 are from Zhou et al.[3], and patients #2 and #4 are from Mithani et al.[5]; and the Adenoid Cystic Carcinoma-ACC patients #5, #6, and #21 are from Mithani et al.[6]. All mutations are scored relative to the rCRS (revised Cambridge Reference Sequence) [20], prefix h indicates heteroplasmy and a suffix indicates a transversion, d-indicates deletion. Tum, Leu, and Lym-indicates Tumor, Leukocyte and Lymphocyte respectively. "Ж" signifies haplogroup specific variants which were found in the patients. Recurrent mutations are underlined. The names of haplogroups are given at the branching points or along single branches. Designation of haplogroups follows van Oven and Kayser [15].

Back to article page