Figure 4
From: Gene expression analysis of cell death induction by Taurolidine in different malignant cell lines
Venn diagram for 55 genes identified by Ingenuity Pathways Analysis ® Ingenuity Pathways Analysis identified 55 Taurolidine regulated genes - in all five cell lines - to be involved in "Cell death", "Cell growth and proliferation" and "Cell cycle" function. The 55 genes were significantly up- or down regulated in all five cell lines with a mean change ≥ 2 fold following Taurolidine (250 μM) treatment compared to control treatment (Povidon 5%). The Venn diagram illustrates the distribution and overlapping of Taurolidine regulated genes among the different functions.