Figure 2
From: Gene expression analysis of cell death induction by Taurolidine in different malignant cell lines
Effects of Taurolidine (TRD) 250 μM on viability, apoptosis and necrosis in different malignant cell lines. HT29, Chang Liver, HT1080, AsPC-1 and BxPC-3 cells were incubated with TRD 250 μM and with Povidon 5% (control) for 24 h. The percentages of viable (a), apoptotic (b) and necrotic cells (c) were determined by FACS-analysis for Annexin V-FITC and Propidiumiodide. Values are means ± SEM of 9 (HT29), 10 (Chang Liver, BxPC-3) or 11 (HT1080, AsPC-1) independent experiments with 4-5 consecutive passages. Asterisk symbols on columns indicate differences between control and TRD treatment. *** p ≤ 0.001, ** p ≤ 0.01, * p ≤ 0.05 (one-way ANOVA followed by Tukey's post-hoc test)