Tumor location (sample ID) | Morphology | Differentiation | Growth pattern | Lymphocytic infiltration | Mucinous | BAX | IGF2R | KRAS | BRAF | MMR protein expression | MMRgermline mutation |
---|---|---|---|---|---|---|---|---|---|---|---|
Rectum (T8) | Exophytic | Moderate/well | Expanding | Moderate | No | Positive | Negative | Negative | Negative | MSH2/MSH6 absence | MSH2 c.388_389del |
Rectum (T20) | Ulcerated | Moderate/well | Expanding | Moderate | No | Negative | Negative | Negative | Negative | Normal | N.a. |
Rectum (T41) | Ulcerated/exophytic | Moderate/well | Expanding | Moderate | Yes | Positive | Positive | Negative | Negative | MSH2/MSH6 absence | Negative |
Sigmoid (T27) | Ulcerated | Well | Infiltrating | Sparse | No | Negative | Negative | Negative | Negative | Normal | N.a. |
Sigmoid (T33) | Ulcerated/exophytic | Moderate/well | Expanding/infiltrating | Sparse | No | Negative | Negative | Positive | Negative | Normal | N.a. |
Sigmoid (T35) | Exophytic | Poor | Infiltrating | Sparse | No | Negative | Negative | Negative | Positive | Normal | N.a. |