Table 2 The 2-year OS and DFS rates associated with ovarian fibrosarcoma patients and Cox proportional hazard regression analysis of patient survival based on clinical and pathologic factors
Variables | Case (%) | 2 year's rate | 2 year's rate | Cox (OS) | Cox (DFS) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Univariate | Multivariate | Univariate | Multivariate | ||||||||||||
OS | X2 | P | DFS | X2 | P | HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | ||
Age (years) | |||||||||||||||
< 45 | 15 (48.4) | 66 | 60 | ||||||||||||
≥ 45 | 16 (51.6) | 45.4 | 0.879 | 0.348 | 27.8 | 1.476 | 0.224 | 1.731 (0.540-5.545) | 0.356 | 1.882 (0.658-5.382) | 0.238 | ||||
FIGO stage | |||||||||||||||
I a - I c | 14 (45.2) | 77.1 | 68.4 | ||||||||||||
II a - III c | 17 (54.8) | 36.2 | 6.041 | 0.014 | 22.9 | 8.964 | 0.003 | 4.525 (1.210-16.916) | 0.025 | 10.156 (2.021-51.023) | 0.005 | 4.914 (1.538-15.704) | 0.007 | 18.761 (1.674-210.288) | 0.017 |
Largest diameter (cm) | |||||||||||||||
< 10 | 11 (45.8) | 43.2 | 44.4 | ||||||||||||
≥ 10 | 13 (54.2) | 54.7 | 0.069 | 0.793 | 38.9 | 0.187 | 0.666 | 0.844 (0.236-3.014) | 0.794 | 1.302 (0.389-4.360) | 0.669 | ||||
Mitoses/10 HPFs | |||||||||||||||
< 4 | 22 (71.0) | 49.7 | 48 | ||||||||||||
≥ 4 | 9 (29.0) | 70 | 0.632 | 0.426 | 41.7 | 0.046 | 0.83 | 0.545 (0.119-2.499) | 0.435 | 1.132 (0.358-3.575) | 0.833 | ||||
Ki-67 (MIB-1)-positive | |||||||||||||||
< 10 | 5 (26.3) | 100 | 66.7 | ||||||||||||
≥ 10 | 14 (73.7) | 27.2 | 4.148 | 0.042 | 36.3 | 3.138 | 0.076 | 51.792 (0.053-5058) | 0.261 | 5.862 (0.668-51.416) | 0.11 | ||||
Therapy | |||||||||||||||
BAO/OR/CT/BAO+RT/OR+RT | 20 (64.5) | 27.9 | 28.5 | ||||||||||||
BAO+CT | 11 (35.5) | 100 | 9.462 | 0.002 | 72.9 | 6.97 | 0.008 | 0.070 (0.008-0.574) | 0.013 | 0.029 (0.003-0.319) | 0.004 | 0.197 (0.052-0.741) | 0.016 | 0.071 (0.005-0.992) | 0.049 |