Inhibition of IKK activity induces TRAIL-mediated Caspase 3 activation in lung cancer cells. Caspase activity assays were performed following co-infection of A549 lung cancer cells with Ad5hTRAIL and AdIKKβKA or AdCMVLacZ vectors. MOI and types of viral vectors used in the infection are provided on the X-axis. AdCMVLacZ construct was used at an MOI of 10,000 DNA particles/cell. Caspase activity was assessed under fluorescent microscopy. Data represent the mean of (± SEM) fıve independent data points. * p < 0.05.