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Table 3 Univariate analysis of local control.

From: Prognostic factors for outcomes after whole-brain irradiation of brain metastases from relatively radioresistant tumors: a retrospective analysis

  At 6 months At 12 months  
  (%) (%) P
Tumor type    
Malignant melanoma 37 5  
Renal cell carcinoma 41 22  
Colorectal cancer 33 14 0.36
WBI schedule    
5 × 4 Gy 42 0  
10 × 3 Gy 20 4  
15 × 3/20 × 2 Gy 53 30 <0.001
Age    
≤ 62 years 42 13  
≥ 63 years 31 18 0.63
Gender    
Female 33 16  
Male 39 14 0.32
Karnofsky Performance Score    
< 70 12 0  
≥ 70 50 23 <0.001
Number of metastases    
1-3 60 28  
≥4 18 0 <0.001
Extracerebral metastases    
No 45 21  
Yes 32 10 0.10
Interval from first diagnosis to WBI    
≤ 24 months 37 10  
≥ 25 months 37 19 0.44
RPA class    
1 80 38  
2 42 18  
3 12 0 <0.001