Figure 7
From: Chemokine-mediated distribution of dendritic cell subsets in renal cell carcinoma
Two-colour immunofluorescence investigation of chemokine and chemokine receptor expression. MIP-3β (Cy2 - green fluorescence) is expressed by CD83+ co-expressing DCs (Cy3 - red fluorescence; A, 600x). In contrast, SLC (Cy3 - red fluorescence) is co-expressed by D2-40+ lymphatic endothelial cells (Cy2 - green fluorescence; B, 400x). Within the lymphatic infiltrates of the tumour border zone CCR7 (Cy3 - red fluorescence) is co-expressed by CD83+ mature DCs (Cy2 - green fluorescence; C, 400x). Negative control (D, 400x).