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Figure 5 | BMC Cancer

Figure 5

From: Chemokine-mediated distribution of dendritic cell subsets in renal cell carcinoma

Figure 5

Real-time RT-PCR analysis of MIP-3α, MIP-3β, and SLC mRNA expression. Total RNA was analyzed for MIP-3α (A), MIP-3β (B), and SLC (C) mRNA expression by quantitative RT-PCR from tissue samples of RCC and corresponding normal kidney tissues of the same patient (n = 10). mRNA isolated from five normal lymph nodes served as positive controls showing abundant transcripts for MIP-3β and SLC, whereas only weak expression for MIP-3α could be observed. RCC tissue demonstrated a significantly increased expression of MIP-3α mRNA compared to the corresponding normal kidney (p = 0.0013). In contrast MIP-3β (p = 0,395) and SLC (p = 0,137) did not prove to be significantly different between tumour tissue and controls.

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