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Figure 2 | BMC Cancer

Figure 2

From: Chemokine-mediated distribution of dendritic cell subsets in renal cell carcinoma

Figure 2

Quantification of CD1a (A) and CD83 (B) expressing dendritic cells (DCs) in RCC tissue, tumour infiltration border zone and corresponding normal kidney. (A) Tumour tissue of RCC shows a statistically significant increased number of immature CD1a+ DCs (Mean: 14.44, SD: 19.59) compared to the tumour infiltration border zone (Mean: 4.621, SD: 5.577) and normal kidney tissue (Mean: 2.182, SD: 1.805). (B) In contrast, a significant increased amount of mature CD83+ DCs is observed within the tumour infiltration border zone (Mean: 18.41, SD: 11.94) compared to tumour tissue (Mean: 4.6608, SD: 4.364) and normal kidney (Mean: 4.784, SD: 3.282; Mann-Whitney test with Bonferroni correction; p values < 0.05 were considered as statistically significant).

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