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Table 3 Dose-intensity

From: "Poker" association of weekly alternating 5-fluorouracil, irinotecan, bevacizumab and oxaliplatin (FIr-B/FOx) in first line treatment of metastatic colorectal cancer: a phase II study

  

All patients

Young-elderly patients

  

DI/cycle mg/m2(or Kg)/w

DI/cycle mg/m2(or Kg)/w

 

Projected DI mg/m2(o Kg)/w

Median (Range)

Received DI (%)

Median (Range)

Received DI (%)

5-FU

1800

1487

82,6

1420

80

  

(480-1800)

 

(480-1800)

 

CPT-11

80

66.7

83

61

76

  

(25-80)

 

(25-80)

 

l-OHP

40

32

80

31.5

79

  

(8-40)

 

(8-40)

 

BEV

2.5

2.1

84

2

80

  

(1-2.5)

 

(1-2.5)

 
  1. Abbreviation: DI, dose-intensity; 5-FU, 5-Fluorouracil; CPT-11, Irinotecan; l-OHP, Oxaliplatin; BEV, Bevacizumab.