Table 2 Novel RASSF1C target genes in T47D breast cancer cells
Gene | Gene discription | Fold change |
|---|---|---|
EFEM1 | EGF-containing fibulin-like extracellular matrix protein 1 | 5.76 |
GHR | growth hormone receptor | 4.3 |
EGR1 | early growth response 1 | 5.9 |
TP53IN1 | tumor protein p53 inducible nuclear protein 1 | 4.46 |
MRAS | muscle RAS oncogene homolog | 3.8 |
MTUS1 | mitochondrial tumor suppressor 1 | -2 |
PROS | protein S (alpha) | 4 |
EMP1 | epithelial membrane protein 1 | -7.5 |
HOXA1 | homeobox A1 | 4.6 |
SEPP1 | selenoprotein P, plasma, 1 | 7.92 |
MGMT | O-6-methylguanine-DNA methyltransferase | 2.1 |
PAK1 | p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) | 2.1 |
CXCR4 | chemokine (C-X-C motif) receptor 4 | 3.6 |
CREG | cellular repressor of E1A-stimulated genes 1 | 11.2 |
BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 2 |
Noggin | Noggin | -3.6 |
SSP1 | (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | -14.5 |
TGM2 | TGM2: transglutaminase 2 (protein-glutamine-gamma-glutamyltransferase) | 3 |
SRPX | sushi-repeat-containing protein, X-linked | -7.25 |
SAMD5 | sterile alpha motif domain containing 5 | -11.47 |
MAP1B | microtubule-associated protein 1B | -11.7 |
RNF182 | ring finger protein 182 | -13.8 |
TMEM8 | transmembrane protein 158 | -11.29 |
LDB2 | LIM domain binding 2 | -5.85 |
IGFBP3 | insulin-like growth factor binding protein 3 | -4.96 |
COL131 | collagen, type XIII, alpha 1 | -8.69 |
FRMDB | FERM domain containing 4B | -5.2 |
SOX9 | SRY (sex determining region Y)-box 9 | -4.5 |
DAB2 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | -2.55 |
APOE | apolipoprotein E | 3.74 |
CCND2 | cyclin D2 | -3 |
SPANX1 | sperm protein associated with the nucleus, X-linked, family member A1 | 7.38 |
SPANX1 | SPANX family, member B1 | 17.7 |
HLADP1 | major histocompatibility complex, class II, DP alpha 1 | 12.7 |
HIST1H2BC | histone cluster 1 H2BC | 5.34 |
DACH1 | dachshund homolog 1 (Drosophila) | 7.63 |
PCDH7 | protocadherin 7 | 8.58 |
MYL9 | myosin, light chain 9, regulatory | 9 |
DPEP3 | dipeptidase 3 | 10.66 |
CPE | carboxypeptidase E | 11.47 |
LITAF | lipopolysaccharide-induced TNF facto | 8.17 |
ABAT | 4-aminobutyrate aminotransferase | 10.82 |