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Table 1 Results of cell cycle analyses in SEM and Jurkat cells

From: The multikinase inhibitor Sorafenib displays significant antiproliferative effects and induces apoptosis via caspase 3, 7 and PARP in B- and T-lymphoblastic cells

  

SEM

Jurkat

Time

Phase

DMSO

0.73 μM

7.30 μM

DMSO

0.73 μM

7.30 μM

24 h

G0/G1

84.6%

87.2%

85.4%

70.4%

72.8%

61.9%

 

S

8.3%

4.2%

8.4%

6.8%

11.7%

18.2%

 

M

7.1%

8.6%

7.2%

22.8%

15.5%

19.9%

48 h

G0/G1

79.6%

93.5%

86.3%

72.2%

57.3%

83.1%

 

S

9.9%

2.3%

3.8%

13.3%

14.7%

6.7%

 

M

10.5%

4.2%

9.9%

14.5%

28.0

10.2%

72 h

G0/G1

84.0%

95.9%

91.6%

75.2%

69.3%

83.0%

 

S

8.7%

2.4%

6.2%

14.0%

18.3%

10.5%

 

M

7.3%

1.7%

2.2%

10.8%

12.4%

6.5%

96 h

G0/G1

79.6%

89.9%

93.2%

67.8%

68.6%

82.9%

 

S

10.7%

4.2%

3.3%

13.5%

17.0%

11.6%

 

M

9.7%

5.9%

3.5%

18.7%

1.4%

5.5%