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Table 3 Cox regression for survival time using the stepwise variable selection method.

From: Differential survival following trastuzumab treatment based on quantitative HER2 expression and HER2 homodimers in a clinic-based cohort of patients with metastatic breast cancer

Variable

Category

Hazard ratio

95% C.I.

P-value

Log10HER2 expression (1)

75 percentile~/50~ 75 percentile

0.25

0.08

0.77

0.019

Log10HER2 expression (2)

25~ 50 percentile/50~ 75 percentile

0.79

0.32

1.97

0.610

Log10HER2 expression (3)

~ 25 percentile/50~ 75 percentile

0.12

0.03

0.51

0.004

Hormone receptor status

+/-

0.18

0.04

0.71

0.014

Brain mets

No/Yes

0.07

0.02

0.24

<.0001