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Table 2 Univariate analysis for overall survival time.

From: Differential survival following trastuzumab treatment based on quantitative HER2 expression and HER2 homodimers in a clinic-based cohort of patients with metastatic breast cancer

Variable

Category

Hazard ratio

95% C.I.

P-value

Treatment group

trastuzumab/trastzumab+chemo

1.24

0.43

3.56

0.693

ER

+/-

0.81

0.28

2.33

0.694

PR

+/-

0.45

0.14

1.49

0.190

Hormone receptor

+/-

0.53

0.19

1.54

0.244

Tumor stage

Recurrence/advanced

3.30

0.45

24.4

0.242

No. of metastatic sites

1/2/3/4

0.54

0.37

0.79

0.002

Liver mets

No/Yes

0.74

0.34

1.59

0.435

Lung mets

No/Yes

0.83

0.40

1.72

0.615

Bone mets

No/Yes

0.42

0.20

0.88

0.021

Lymph node mets

No/Yes

1.02

0.49

2.14

0.959

Brain mets

No/Yes

0.18

0.07

0.46

<.0001