Triple negativity and young age as prognostic factors in lymph node-negative invasive ductal carcinoma of 1 cm or less

Table 2 Number of events and five year recurrence free survival according to prognostic factors.

Variable		No. of patients	No. of events	Proportion surviving to 5 years (%)	p value
T stage
	T1mic	120	4	97.4	0.681
	T1a	93	2	97.8
	T1b	162	6	96.9
Age
	≤ 35	23	3	90.9	0.002
	>35	352	9	97.7
Grade^¶
	1 (low)	28	1	96.3	0.696
	2	152	5	96.6
	3 (high)	71	2	98.6
ER^a
	negative	136	7	95.1	0.123
	positive	237	5	98.2
PR^b
	negative	187	9	96.0	0.126
	positive	186	3	98.2
HR
	ER-PR-	122	7	94.9	0.069
	ER+ and/or PR+	251	5	98.4
HER2^c
	Negative	276	8	97.4	0.772
	Positive	96	3	97.9
HR/HER2
	HR+HER2-	220	4	98.6	0.225
	HR+HER2+	31	1	96.8
	HR-HER2+	65	2	98.5
	HR-HER2-	56	4	92.6
HR/HER2
	HR+ and/or HER2+	316	7	98.4	0.018
	HR-HER2-	56	4	92.6
p53^d
	<10%;	220	4	97.9	0.543
	≥10%	143	6	97.1
Ki-67^d
	<10%	275	6	98.4	0.148
	≥10%	88	4	95.5

^¶ Only T1a, T1b patients were analyzed using nuclear/histolgogic grade.
^a,bData of hormone receptor status was available in 373 patients. ;<10%;negative, ≥10%;positive
^c HER2 status was determined by immunohistochemistry and was available in 372 patients.; 0,1+,2+;negative, 3+;positive
^dData of p53 and i-67 was available in 363 patients.

ISSN: 1471-2407