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Table 1 Baseline characteristics of all patients according to T stage

From: Triple negativity and young age as prognostic factors in lymph node-negative invasive ductal carcinoma of 1 cm or less

 

All patients

T1mic

T1a

T1b

 
 

(N = 375)

(N = 120)

(N = 93)

(N = 162)

P value

Age at diagnosis

     

   Median

49

49

47

50

0.297

   Range

24 - 77

27 - 74

29 - 77

24 - 73

 

Grade¶

     

   1

28(11.2)

.

8(9.0)

20(12.3)

0.126

   2

152(60.6)

.

49(55.0)

103(63.6)

 

   3

71(28.3)

.

32(36.0)

39(24.1)

 

ERa

     

   Negative

136(36.5)

68(57.6)

32(34.4)

36(22.2)

<0.001

   Positive

237(63.5)

50(42.4)

61(65.6)

126(77.8)

 

PRb

     

   Negative

187(50.1)

81(68.6)

45(48.4)

61(37.7)

<0.001

   Positive

186(49.9)

37(31.4)

48(51.6)

101(62.3)

 

HER2c

     

   Negative

276(74.2)

64(54.2)

71(77.2)

141(87.0)

<0.001

   Positive

96(25.8)

54(45.8)

21(22.8)

21(13.0)

 

HR/HER2

     

   HR+HER2-

220(59.1)

42(35.6)

56(60.9)

122(75.3)

<0.001

   HR+HER2+

31(8.3)

11(9.3)

9(9.8)

11(6.8)

 

   HR-HER2+

65(17.5)

43(36.4)

12(13)

10(6.2)

 

   HR-HER2-

56(15.1)

22(18.6)

15(16.3)

19(11.7)

 

p53d

     

   <10%

220(60.6)

60(52.2)

56(63.6)

104(65.0)

0.080

   ≥10%

143(39.4)

55(47.8)

32(36.4)

56(35.0)

 

Ki-67d

     

   <10%

275(75.8)

82(71.3)

72(81.8)

121(75.6)

0.223

   ≥10%

88(24.2)

33(28.7)

16(18.2)

39(24.4)

 
  1. ¶ Nuclear/histologic grade was assessed only in T1a and T1b patients.
  2. a,bData of hormone receptor status was available in 373 patients. ;<10%;negative, ≥10%;positive
  3. c HER2 status was determined by immunohistochemistry and was available in 372 patients.; 0,1+,2+;negative, 3+;positive
  4. dData of p53 and Ki-67 was available in 363 patients.
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BMC Cancer

ISSN: 1471-2407

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