Figure 2
From: Anti-apoptotic effect of claudin-1 in tamoxifen-treated human breast cancer MCF-7 cells
The mRNA levels of claudin-1 were increased in MCF-7 cells treated with tamoxifen. (A) After the MCF-7 and T47 D cells had been treated with various concentrations of tamoxifen for 20 h and subjected to RT-PCR analyses. One representative of at least three independent experiments with similar results is shown. (B) MCF-7 and T47 D cells were treated with or without 40 μM of tamoxifen for 20 h, and subjected to real-time PCR analyses for claudin-1 and E-cadherin. Each value represents the mean + SE (bars) of three independent experiments *p < 0.05, according to the t-test.