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Table 2 Co-expression frequency and association between protein expressions

From: Genome profiling of ERBB2-amplified breast cancers

Protein combinations

Co-expression*

 

N (%)

pERBB2/ERBB2

81% (17/21)

IGF1R/ERBB2

24% (7/29)

IGF1R/pERBB2

14% (2/14)

EGFR/ERBB2

33% (12/36)

EGFR/pERBB2

41% (7/17)

IGF1R/EGFR

11% (1/9)

IGF1R and EGFR/ERRB2

3% (1/29)

IGF1R and EGFR/pERBB2

0% (0/14)

FOXA1/ERBB2

67% (14/21)

FOXA1/pERBB2

71% (12/17)

  1. *Co-expression means that tumors were positive for both factors. †Expression scores evaluated according to scales defined in material and methods to examine correlations.