Table 2 Univariate and multivariate Cox regression analysis of different prognostic varibles in patients with NPC
From: LATS2 is De-methylated and Overexpressed in Nasopharyngeal Carcinoma and Predicts Poor Prognosis
Variable | Subset | Hazard ratio (95% CI) | P |
|---|---|---|---|
Univariate analysis (n = 220) | |||
LATS2 expression | High vs. Low | 1.978(1.207-3.241) | 0.007 |
Age | < 46 vs. ≥46 | 1.563(0.957-2.552) | 0.075 |
Gender | Male vs. Female | 0.380(0.193-0.746) | 0.005 |
Clinical stage | I, II vs. III, IV | 1.717(0.932-3.165) | 0.083 |
T-stage | T1+T2 vs. T3+T4 | 1.477(0.889-2.457) | 0.132 |
N-stage | N0 vs. N1+N2+N3 | 0.888(0.525-1.502) | 0.658 |
Histological type (WHO) | II vs. III | 1.064(0.624-1.815) | 0.820 |
Recurrence | No vs. Yes | 1.468(0.891-2.418) | 0.132 |
Metastasis | No vs. Yes | 2.578(1.424-4.665) | 0.002 |
Multivariate analysis (n = 220) | |||
LATS2 expression | High vs. Low | 1.714(1.033-2.843) | 0.037 |
Gender | Male vs. Female | 0.437(0.219-0.874) | 0.019 |
Metastasis | No vs. Yes | 2.677(1.424-5.031) | 0.002 |