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Table 2 Univariate analysis of prognostic factors by log-rank test

From: Application of tumor-node-metastasis staging 2002 version in locally advanced hepatocellular carcinoma: is it predictive of surgical outcome?

Variable Cases 1y-OS(%) 3y-OS(%) 5y-OS(%) P
Gender      0.913
   Female 22 45.5 31.8 18.2  
   Male 276 59.1 25.9 15.9  
Age (years)      0.079
   ≤48 146 54.7 22.9 13.7  
   >48 152 60.5 29.6 18.3  
HBsAg      0.269
   Negative 41 58.7 37.6 18.8  
   Positive 257 56.5 23.2 14.9  
HCVAb      0.380
   Negative 280 55.2 27.3 18.2  
   Positive 18 47.5 22.0 12.9  
ALB (g/L)      0.004
   ≤35 37 42.3 7.7 0.0  
   >35 261 59.6 27.7 17.3  
TBIL (μmol/L)      0.879
   ≤20 204 62.8 29.3 16.0  
   >20 94 58.0 28.0 14.3  
PT (s)      0.185
   ≤13.5 148 62.0 32.9 22.3  
   >13.5 150 57.0 24.6 14.4  
ICGR15 (%)      0.423
   ≤10 155 52.2 26.7 17.8  
   >10 143 61.7 28.2 19.4  
AFP (μg/L)      0.112
   ≤25 48 63.2 34.3 20.5  
   >25 250 56.0 25.8 16.0  
Child-Pugh      0.275
   A 260 59.4 27.4 16.5  
   B 38 50.0 18.8 12.5  
MELD      0.243
   ≤7 169 58.0 24.7 13.9  
   >7 129 57.2 32.6 20.7  
Cirrhosis      0.028
   No 57 61.0 39.5 26.6  
   Yes 241 57.8 23.5 13.8  
Tumor size(cm)      0.278
   ≤5 35 66.0 31.0 21.0  
   >5 263 56.0 23.5 14.5  
Variable Cases 1y-OS(%) 3y-OS(%) 5y-OS(%) P
Tumor number      0.101
   Solitary 108 59.7 33.3 23.3  
   Multiple 190 57.8 23.1 12.5  
Tumor location      0.126
   Unilobar 255 52.7 27.2 17.3  
   Bilobar 43 45.2 21.4 10.0  
Tumor encapsulation      0.093
   Yes 87 54.1 26.1 18.1  
   No 211 44.1 17.0 12.0  
Microvascular invasion      0.117
   No 111 56.5 24.0 16.7  
   Yes 187 48.1 19.4 11.0  
Major vascular invasion      <0.001
   No 237 65.2 32.2 19.6  
   Yes 61 29.7 0.0 0.0  
Invasion of adjacent organs      0.197
   No 219 59.9 27.7 16.0  
   Yes 69 56.3 17.0 12.4  
Perforation of visceral peritoneum      0.295
   No 220 60.1 26.9 18.4  
   Yes 78 53.8 21.0 13.6  
Resection margin(mm)      0.201
   0 188 49.3 20.8 12.7  
   >0 110 58.4 26.1 17.9  
Resection extent      0.062
   Major 217 54.7 23.5 15.2  
   Minor 81 67.9 28.0 18.9  
Blood loss(L)      0.140
   ≤0.8 163 62.8 30.5 21.5  
   >0.8 135 52.9 21.2 12.9  
Blood transfusion      0.488
   No 142 59.0 26.3 17.6  
   Yes 157 57.9 26.6 14.4  
Previous TACE      0.724
   No 282 57.3 27.1 16.4  
   Yes 16 48.4 21.3 13.2  
Postoperative adjuvant TACE      0.923
   No 222 61.7 28.6 15.5  
   Yes 76 53.2 23.0 15.2