HER2 testing on core needle biopsy specimens from primary breast cancers: interobserver reproducibility and concordance with surgically resected specimens

Table 6 Concordance of consensus HER2 FISH results of between core needle biopsy and surgically resected specimens.

HER2/CEP17ratio for surgically resected specimens	Number of tumors
	HER2/CEP17ratio for CNB specimens
	> 2.2	1.8 to 2.2	<1.8
Higher than 2.2	11	0	1
1.8 to 2.2	0	0	0
<1.8	1	0	12
% agreement = 92%

The judgments were performed according to the 2007 ASCO/CAP guideline. For two tumors, data on CNB and/or surgically resected specimens were not available.

ISSN: 1471-2407