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Table 3 Estimated haplotype frequencies and association significance

From: Polymorphisms of XRCC4 are involved in reduced colorectal cancer risk in Chinese schizophrenia patients

Haplotype*

Haplotype frequency(%)

X2

pvalue

Odds Ratio (95%CI)

rs6452526

rs2662238

rs963248

rs35268

rs2386275

CRC

SZ

   

T

A

   

63.97(13.0)

98.00(20.2)

8.251

0.004

0.61(0.43-0.86)

C

G

   

415.97(84.2)

386.00(79.8)

8.251

0.004

1.65(1.17-2.33)

  

G

C

 

40.64(8.1)

61.29(12.5)

5.118

0.024

0.62(0.41-0.94)

T

A

G

T

A

18.46(5.2)

45.45(10.2)

6.693

0.010

0.48(0.28-0.85)

T

A

G

C

A

5.22(1.5)

20.07(4.5)

5.918

0.015

0.32(0.12-0.84)

C

G

A

T

G

54.49(15.2)

36.21(8.2)

10.445

0.001

2.07(1.32-3.24)

  1. *Haplotypes were omitted from analysis if the estimated haplotype probabilities were less than 5%
  2. CI = confidence interval, CRC = colorectal cancer, SZ = schizophrenia.
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BMC Cancer

ISSN: 1471-2407

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