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Table 1 Univariate Analyses of TF and Tn Expression in Women With an Abnormal (Atypia or Cancer) vs. a Benign Breast Biopsy

From: Carbohydrate antigens in nipple aspirate fluid predict the presence of atypia and cancer in women requiring diagnostic breast biopsy

   Overall Benign1 Abnormal1 P value2
All Subjects (N)   124 34 90  
TF Log10 Mean (SD) .65 (.54) .46 (.48) .72 (.54) .016
  Median 1.87 1.19 4.20 .015
  Geometric Mean (SD) 8.55 (12.73) 5.63 (12.3) 9.65 (12.78) .12
Tn Log10 Mean (SD) .59 (.50) .54 (.50) .60 (.50) .51
  Median 2.87 1.29 3.12 .57
  Geometric Mean (SD) 6.47 (9.52) 5.77 (8.48) 6.73 (9.92) .62
Premenopausal (N)   52 18 34  
TF Log10 Mean (SD) .71 (.54) .61 (.59) .76 (.52) .34
  Median 4.53 1.66 7.71 .27
  Geometric Mean (SD) 9.44 (12.48) 9.6 (16.04) 9.36 (10.4) .95
Tn Log10 Mean (SD) .58 (.46) .48 (.49) .64 (.45) .24
  Median 3.25 .97 3.70 .25
  Geometric Mean (SD) 5.51 (7.33) 4.71 (7.32) 5.94 (7.4) .57
Postmenopausal (N)   72 16 56  
TF Log10 Mean (SD) .60 (.53) .29 (.21) .69 (.56) .007
  Median 1.61 1.19 2.44 .014
  Geometric Mean (SD) 7.91 (12.96) 1.17 (1.03) 9.83 (14.12) .000
Tn Log10 Mean (SD) .59 (.53) .61 (.52) .58 (.54) .88
  Median 1.94 1.47 2.44 .71
  Geometric Mean (SD) 7.16 (10.83) 6.96 (9.73) 7.21 (11.21) .94
  1. 1: Benign = normal and hyperplasia; Abnormal = atypical hyperplasia, ductal carcinoma in situ and invasive cancer. TF and Tn median results are in Abs/μL.
  2. 2: P value for Log10 and geometric means are based on the t-test; P value for medians are based on the Mann-Whitney-Wilcoxon test.